--- title: "Medellin (MDE) to Guayaquil (GYE) flights: who flies it" description: "Avianca flies Medellin (MDE) to Guayaquil (GYE) nonstop about 3 times a week as AV 8399, scheduled at 1h 55m. See the full timetable and who flies it on 2LNR." canonical: "https://2lnr.com/routes/mde-gye" url: "https://2lnr.com/routes/mde-gye.md" date_modified: "2026-10-25T05:37:10Z" --- # Medellin to Guayaquil (MDE-GYE): nonstop flights and who flies them Avianca flies nonstop from Medellin (MDE) to Guayaquil (GYE) just three times a week. In the timetable below it flies as AV 8399, scheduled at 1h 55m for the 651 miles. Schedule last confirmed October 25, 2026. Departure times come from 2LNR's schedule data; confirm with the airline before you book. Updated October 28, 2026. See MDE to GYE on the interactive map [Get started free](https://2lnr.com/login) 3 Flights a week, 4-week average 1h 55m Scheduled flight time 651 mi Nonstop distance Free To get started ## Medellin to Guayaquil flight schedule Scheduled nonstop departures for MDE to GYE starting October 28, 2026, last checked against our schedule feed on October 25, 2026. Airlines retime and cancel flights, so confirm with the airline before you book. Scheduled nonstop departures from Medellin (MDE) to Guayaquil (GYE) | Date | Flight | Airline | Departs MDE | Arrives GYE | Duration | Aircraft | | :--- | :--- | :--- | :--- | :--- | :--- | :--- | | Wed, Oct 28 | AV 8399 | Avianca | 16:50 | 18:45 | 1h 55m | [Airbus A320](https://2lnr.com/seatmaps/av/a320.md) | | Fri, Oct 30 | AV 8399 | Avianca | 16:50 | 18:45 | 1h 55m | [Airbus A320neo](https://2lnr.com/seatmaps/av/a320neo.md) | | Mon, Nov 2 | AV 8399 | Avianca | 16:50 | 18:45 | 1h 55m | Airbus A320neo | | Wed, Nov 4 | AV 8399 | Avianca | 16:50 | 18:45 | 1h 55m | Airbus A320neo | | Fri, Nov 6 | AV 8399 | Avianca | 16:50 | 18:45 | 1h 55m | Airbus A320neo | | Mon, Nov 9 | AV 8399 | Avianca | 16:50 | 18:45 | 1h 55m | Airbus A320neo | | Wed, Nov 11 | AV 8399 | Avianca | 16:50 | 18:45 | 1h 55m | Airbus A320neo | Showing all 7 scheduled MDE to GYE departures across 7 days with service, starting October 28, 2026. Later dates are on the interactive map. Departure and arrival times are local at their own airport, so an arrival can fall on a different local date than the departure; the duration column is the true elapsed flying time. A dash means the airline hasn't filed that value in the schedule data we hold. Aircraft are the equipment the airline filed, named where the code pins down one type and shown as the family or the bare code where it doesn't. Swaps can happen up to departure. See every MDE to GYE date on the interactive map ## Aircraft on the Medellin to Guayaquil nonstop Avianca flies the departures in the schedule table on this page with the [Airbus A320neo](https://2lnr.com/seatmaps/av/a320neo.md) and the [Airbus A320](https://2lnr.com/seatmaps/av/a320.md). Each linked aircraft page shows where that airline schedules it. Airlines can swap aircraft up to departure. ## The full MDE to GYE nonstop schedule This page carries the full MDE to GYE nonstop schedule, who operates each departure and how often it runs; the reverse direction is linked below. ### See the schedule Who operates each MDE to GYE nonstop and how often it runs, from 2LNR's schedule data. ### Plan on the map See MDE to GYE on the interactive route map, with schedules, connections, and route statistics. ## Airlines flying Medellin to Guayaquil nonstop Carriers operating MDE to GYE nonstop in the current schedule. - [Avianca (AV) route map](https://2lnr.com/routes/airlines/av.md)\ [The aircraft AV flies](https://2lnr.com/seatmaps/av.md) See MDE to GYE on the interactive map → ## Frequently asked questions about MDE to GYE **How long is the flight from Medellin (MDE) to Guayaquil (GYE)?** AV 8399 is scheduled at 1h 55m from Medellin (MDE) to Guayaquil (GYE) on every departure in the schedule table on this page. The nonstop covers about 651 miles, and airlines adjust scheduled times by season, so confirm with the airline before you book. **Which airlines fly nonstop from MDE to GYE?** Avianca is currently the only airline flying MDE to GYE nonstop. 2LNR doesn't show award or upgrade space for it on MDE to GYE, so this page carries the schedule rather than a space claim. **How often does MDE to GYE operate?** The MDE to GYE nonstop currently runs three times a week, on Avianca. Thin schedules like this change by season, and on Pro an alert will catch anything added. **What time do flights from MDE to GYE depart?** In the next 7 days with service, every scheduled MDE to GYE nonstop leaves at 16:50 local time at Medellin. The schedule table on this page lists each departure by date. **Which flights operate MDE to GYE nonstop?** Avianca flies AV 8399 nonstop from Medellin (MDE) to Guayaquil (GYE), the only flight number in the schedule table on this page. The table lists each date with its departure and arrival times and aircraft. **Does 2LNR show upgrade or award space on MDE to GYE?** Not on this route: 2LNR doesn't show award or upgrade space for Avianca on MDE to GYE. The page carries the full MDE to GYE nonstop schedule and who flies each departure, and the reverse direction is linked below. Flying the other way? See [GYE to MDE nonstop flights](https://2lnr.com/routes/gye-mde.md). Award seats rather than schedules? See [award availability by airline](https://2lnr.com/awards.md). Looking beyond this route? See [every route from Medellin (MDE)](https://2lnr.com/routes/mde.md), or [every route from Guayaquil (GYE)](https://2lnr.com/routes/gye.md). Nonstops to Guayaquil (GYE) from other airports within 150 miles of Medellin (MDE): - [Bogota (BOG) to Guayaquil (GYE)](https://2lnr.com/routes/bog-gye.md), 134 miles from MDE Distances are great-circle between the airports, not driving distance. - [How to plan an upgrade by route](https://2lnr.com/guides/upgrade-strategy.md) ## See the full MDE to GYE nonstop schedule Every scheduled departure on this route, with who flies it. 2LNR shows upgrade and award space by date on the carriers it tracks, the next 14 days free on every product and the full horizon on Pro. [Get started free](https://2lnr.com/login)