---
title: "Panama City to Medellin flights: who flies PTY-MDE"
description: "Copa Airlines flies Panama City (PTY) to Medellin (MDE) nonstop about 56 times a week, scheduled at 1h 25m to 1h 26m. See the full timetable and who flies it on 2LNR."
canonical: "https://2lnr.com/routes/pty-mde"
url: "https://2lnr.com/routes/pty-mde.md"
date_modified: "2026-10-18T05:10:47Z"
---

# Panama City to Medellin (PTY-MDE): nonstop flights and who flies them

Copa Airlines flies nonstop between Panama City (PTY) and Medellin (MDE), roughly 56 times a week. The timetable below shows the nonstop scheduled at 1h 25m to 1h 26m for the 337 miles.

Schedule last confirmed October 18, 2026. Departure times come from 2LNR's schedule data; confirm with the airline before you book.

Updated October 23, 2026.

See PTY to MDE on the interactive map [Get started free](https://2lnr.com/login)

56

Flights a week, 4-week average

1h 25m to 1h 26m

Scheduled flight time

337 mi

Nonstop distance

Free

To get started

## Panama City to Medellin flight schedule

Scheduled nonstop departures for PTY to MDE starting October 23, 2026, last checked against our schedule feed on October 18, 2026. Airlines retime and cancel flights, so confirm with the airline before you book.

Scheduled nonstop departures from Panama City (PTY) to Medellin (MDE)

| Date | Flight | Airline | Departs PTY | Arrives MDE | Duration | Aircraft |
| :--- | :--- | :--- | :--- | :--- | :--- | :--- |
| Fri, Oct 23 | CM 150 | Copa Airlines | 06:50 | 08:15 | 1h 25m | [Boeing 737-800](https://2lnr.com/seatmaps/cm/737-800.md) |
| Fri, Oct 23 | CM 397 | Copa Airlines | 09:30 | 10:55 | 1h 25m | [Boeing 737 MAX 9](https://2lnr.com/seatmaps/cm/737-max-9.md) |
| Fri, Oct 23 | CM 654 | Copa Airlines | 12:50 | 14:15 | 1h 25m | Boeing 737-800 |
| Fri, Oct 23 | CM 156 | Copa Airlines | 15:30 | 16:55 | 1h 25m | Boeing 737-800 |
| Fri, Oct 23 | CM 208 | Copa Airlines | 18:29 | 19:55 | 1h 26m | Boeing 737-800 |
| Fri, Oct 23 | CM 163 | Copa Airlines | 19:10 | 20:35 | 1h 25m | Boeing 737-800 |
| Fri, Oct 23 | CM 155 | Copa Airlines | 21:25 | 22:50 | 1h 25m | [Boeing 737-700](https://2lnr.com/seatmaps/cm/737-700.md) |
| Sat, Oct 24 | CM 150 | Copa Airlines | 06:50 | 08:15 | 1h 25m | Boeing 737-800 |
| Sat, Oct 24 | CM 756 | Copa Airlines | 08:15 | 09:40 | 1h 25m | Boeing 737 MAX 9 |
| Sat, Oct 24 | CM 397 | Copa Airlines | 09:30 | 10:55 | 1h 25m | Boeing 737 MAX 9 |
| Sat, Oct 24 | CM 654 | Copa Airlines | 12:50 | 14:15 | 1h 25m | Boeing 737-800 |
| Sat, Oct 24 | CM 764 | Copa Airlines | 13:20 | 14:45 | 1h 25m | Boeing 737-800 |
| Sat, Oct 24 | CM 156 | Copa Airlines | 15:30 | 16:55 | 1h 25m | Boeing 737 MAX 9 |
| Sat, Oct 24 | CM 208 | Copa Airlines | 18:35 | 20:00 | 1h 25m | Boeing 737-800 |
| Sat, Oct 24 | CM 155 | Copa Airlines | 21:25 | 22:50 | 1h 25m | Boeing 737-700 |
| Sun, Oct 25 | CM 150 | Copa Airlines | 06:50 | 08:15 | 1h 25m | Boeing 737-800 |
| Sun, Oct 25 | CM 397 | Copa Airlines | 09:30 | 10:55 | 1h 25m | Boeing 737 MAX 9 |
| Sun, Oct 25 | CM 654 | Copa Airlines | 12:50 | 14:15 | 1h 25m | Boeing 737-800 |
| Sun, Oct 25 | CM 156 | Copa Airlines | 15:35 | 17:00 | 1h 25m | Boeing 737 MAX 9 |
| Sun, Oct 25 | CM 208 | Copa Airlines | 18:29 | 19:55 | 1h 26m | Boeing 737-800 |
| Sun, Oct 25 | CM 163 | Copa Airlines | 19:10 | 20:35 | 1h 25m | Boeing 737-800 |
| Sun, Oct 25 | CM 155 | Copa Airlines | 21:25 | 22:50 | 1h 25m | Boeing 737-700 |
| Mon, Oct 26 | CM 150 | Copa Airlines | 06:50 | 08:15 | 1h 25m | Boeing 737 MAX 9 |
| Mon, Oct 26 | CM 756 | Copa Airlines | 08:20 | 09:45 | 1h 25m | Boeing 737-800 |
| Mon, Oct 26 | CM 397 | Copa Airlines | 09:30 | 10:55 | 1h 25m | Boeing 737 MAX 9 |
| Mon, Oct 26 | CM 654 | Copa Airlines | 12:50 | 14:15 | 1h 25m | Boeing 737-800 |
| Mon, Oct 26 | CM 764 | Copa Airlines | 13:20 | 14:45 | 1h 25m | Boeing 737-800 |
| Mon, Oct 26 | CM 156 | Copa Airlines | 15:35 | 17:00 | 1h 25m | Boeing 737 MAX 9 |
| Mon, Oct 26 | CM 208 | Copa Airlines | 18:35 | 20:00 | 1h 25m | Boeing 737-800 |
| Mon, Oct 26 | CM 155 | Copa Airlines | 21:25 | 22:50 | 1h 25m | Boeing 737-700 |
| Tue, Oct 27 | CM 150 | Copa Airlines | 06:50 | 08:15 | 1h 25m | Boeing 737-800 |
| Tue, Oct 27 | CM 756 | Copa Airlines | 08:20 | 09:45 | 1h 25m | Boeing 737-800 |
| Tue, Oct 27 | CM 397 | Copa Airlines | 09:30 | 10:55 | 1h 25m | Boeing 737 MAX 9 |
| Tue, Oct 27 | CM 654 | Copa Airlines | 12:50 | 14:15 | 1h 25m | Boeing 737-800 |
| Tue, Oct 27 | CM 764 | Copa Airlines | 13:20 | 14:45 | 1h 25m | Boeing 737-800 |
| Tue, Oct 27 | CM 156 | Copa Airlines | 15:35 | 17:00 | 1h 25m | Boeing 737-800 |
| Tue, Oct 27 | CM 208 | Copa Airlines | 18:35 | 20:00 | 1h 25m | Boeing 737-800 |
| Tue, Oct 27 | CM 155 | Copa Airlines | 21:25 | 22:50 | 1h 25m | Boeing 737-800 |
| Wed, Oct 28 | CM 150 | Copa Airlines | 06:50 | 08:15 | 1h 25m | Boeing 737-800 |
| Wed, Oct 28 | CM 756 | Copa Airlines | 08:20 | 09:45 | 1h 25m | Boeing 737-800 |

Showing the first 40 of 55 scheduled PTY to MDE departures across 7 days with service, starting October 23, 2026. Every remaining date is on the interactive map.

Departure and arrival times are local at their own airport, so an arrival can fall on a different local date than the departure; the duration column is the true elapsed flying time. A dash means the airline hasn't filed that value in the schedule data we hold. Aircraft are the equipment the airline filed, named where the code pins down one type and shown as the family or the bare code where it doesn't. Swaps can happen up to departure.

See every PTY to MDE date on the interactive map

## Aircraft on the Panama City to Medellin nonstop

Copa Airlines flies the departures in the schedule table on this page with the [Boeing 737-800](https://2lnr.com/seatmaps/cm/737-800.md), the [Boeing 737 MAX 9](https://2lnr.com/seatmaps/cm/737-max-9.md), and the [Boeing 737-700](https://2lnr.com/seatmaps/cm/737-700.md). Each linked aircraft page shows where that airline schedules it. Airlines can swap aircraft up to departure.

## The full PTY to MDE nonstop schedule

This page carries the full PTY to MDE nonstop schedule, who operates each departure and how often it runs; the reverse direction is linked below.

### See the schedule

Who operates each PTY to MDE nonstop and how often it runs, from 2LNR's schedule data.

### Plan on the map

See PTY to MDE on the interactive route map, with schedules, connections, and route statistics.

## Airlines flying Panama City to Medellin nonstop

Carriers operating PTY to MDE nonstop in the current schedule.

- [Copa Airlines (CM) route map](https://2lnr.com/routes/airlines/cm.md)\
  [The aircraft CM flies](https://2lnr.com/seatmaps/cm.md)

See PTY to MDE on the interactive map →

## Frequently asked questions about PTY to MDE

**How long is the flight from Panama City (PTY) to Medellin (MDE)?**

Scheduled flight times from Panama City (PTY) to Medellin (MDE) run from 1h 25m to 1h 26m across the departures in the schedule table on this page. The nonstop covers about 337 miles, and airlines adjust scheduled times by season, so confirm with the airline before you book.

**Which airlines fly nonstop from PTY to MDE?**

Copa Airlines is currently the only airline flying PTY to MDE nonstop. 2LNR doesn't show award or upgrade space for it on PTY to MDE, so this page carries the schedule rather than a space claim.

**How many flights a week are there from PTY to MDE?**

About 56 nonstop flights a week run between Panama City (PTY) and Medellin (MDE) in the current schedule, operated by Copa Airlines. Frequency shifts by season, and the schedule table on this page shows what is scheduled next.

**What time do flights from PTY to MDE depart?**

Scheduled PTY to MDE nonstops in the next 7 days with service leave between 06:50 and 21:25, local time at Panama City. The schedule table on this page lists every departure by date, with its arrival time and aircraft.

**Which flights operate PTY to MDE nonstop?**

The schedule table on this page lists 9 flight numbers for PTY to MDE nonstops, including CM 150, CM 155, CM 156, CM 208, CM 397, CM 654, CM 756, and CM 764 on Copa Airlines. The table lists each departure by date with its times and aircraft.

**Does 2LNR show upgrade or award space on PTY to MDE?**

Not on this route: 2LNR doesn't show award or upgrade space for Copa Airlines on PTY to MDE. The page carries the full PTY to MDE nonstop schedule and who flies each departure, and the reverse direction is linked below.

Flying the other way? See [MDE to PTY nonstop flights](https://2lnr.com/routes/mde-pty.md).

Award seats rather than schedules? See [award availability by airline](https://2lnr.com/awards.md).

Looking beyond this route? See [every route from Panama City (PTY)](https://2lnr.com/routes/pty.md), or [every route from Medellin (MDE)](https://2lnr.com/routes/mde.md).

Nonstops from Panama City (PTY) to other airports within 150 miles of Medellin (MDE):

- [Panama City (PTY) to Pereira (PEI)](https://2lnr.com/routes/pty-pei.md), 96 miles from MDE
- [Panama City (PTY) to Bogota (BOG)](https://2lnr.com/routes/pty-bog.md), 134 miles from MDE

Distances are great-circle between the airports, not driving distance.

- [How to plan an upgrade by route](https://2lnr.com/guides/upgrade-strategy.md)

## See the full PTY to MDE nonstop schedule

Every scheduled departure on this route, with who flies it. 2LNR shows upgrade and award space by date on the carriers it tracks, the next 14 days free on every product and the full horizon on Pro.

[Get started free](https://2lnr.com/login)
