Panama City to Medellin (PTY-MDE): nonstop flights and who flies them

Copa Airlines flies nonstop between Panama City (PTY) and Medellin (MDE), roughly 56 times a week. The timetable below shows the nonstop scheduled at 1h 25m to 1h 26m for the 337 miles.

Schedule last confirmed . Departure times come from 2LNR's schedule data; confirm with the airline before you book.

Updated .

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56
Flights a week, 4-week average
1h 25m to 1h 26m
Scheduled flight time
337 mi
Nonstop distance
Free
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Panama City to Medellin flight schedule

Scheduled nonstop departures for PTY to MDE starting October 23, 2026, last checked against our schedule feed on October 18, 2026. Airlines retime and cancel flights, so confirm with the airline before you book.

Schedule data dated .

Scheduled nonstop departures from Panama City (PTY) to Medellin (MDE)
Date Flight Airline Departs PTY Arrives MDE Duration Aircraft
CM 150Copa Airlines06:5008:151h 25mBoeing 737-800
CM 397Copa Airlines09:3010:551h 25mBoeing 737 MAX 9
CM 654Copa Airlines12:5014:151h 25mBoeing 737-800
CM 156Copa Airlines15:3016:551h 25mBoeing 737-800
CM 208Copa Airlines18:2919:551h 26mBoeing 737-800
CM 163Copa Airlines19:1020:351h 25mBoeing 737-800
CM 155Copa Airlines21:2522:501h 25mBoeing 737-700
CM 150Copa Airlines06:5008:151h 25mBoeing 737-800
CM 756Copa Airlines08:1509:401h 25mBoeing 737 MAX 9
CM 397Copa Airlines09:3010:551h 25mBoeing 737 MAX 9
CM 654Copa Airlines12:5014:151h 25mBoeing 737-800
CM 764Copa Airlines13:2014:451h 25mBoeing 737-800
CM 156Copa Airlines15:3016:551h 25mBoeing 737 MAX 9
CM 208Copa Airlines18:3520:001h 25mBoeing 737-800
CM 155Copa Airlines21:2522:501h 25mBoeing 737-700
CM 150Copa Airlines06:5008:151h 25mBoeing 737-800
CM 397Copa Airlines09:3010:551h 25mBoeing 737 MAX 9
CM 654Copa Airlines12:5014:151h 25mBoeing 737-800
CM 156Copa Airlines15:3517:001h 25mBoeing 737 MAX 9
CM 208Copa Airlines18:2919:551h 26mBoeing 737-800
CM 163Copa Airlines19:1020:351h 25mBoeing 737-800
CM 155Copa Airlines21:2522:501h 25mBoeing 737-700
CM 150Copa Airlines06:5008:151h 25mBoeing 737 MAX 9
CM 756Copa Airlines08:2009:451h 25mBoeing 737-800
CM 397Copa Airlines09:3010:551h 25mBoeing 737 MAX 9
CM 654Copa Airlines12:5014:151h 25mBoeing 737-800
CM 764Copa Airlines13:2014:451h 25mBoeing 737-800
CM 156Copa Airlines15:3517:001h 25mBoeing 737 MAX 9
CM 208Copa Airlines18:3520:001h 25mBoeing 737-800
CM 155Copa Airlines21:2522:501h 25mBoeing 737-700
CM 150Copa Airlines06:5008:151h 25mBoeing 737-800
CM 756Copa Airlines08:2009:451h 25mBoeing 737-800
CM 397Copa Airlines09:3010:551h 25mBoeing 737 MAX 9
CM 654Copa Airlines12:5014:151h 25mBoeing 737-800
CM 764Copa Airlines13:2014:451h 25mBoeing 737-800
CM 156Copa Airlines15:3517:001h 25mBoeing 737-800
CM 208Copa Airlines18:3520:001h 25mBoeing 737-800
CM 155Copa Airlines21:2522:501h 25mBoeing 737-800
CM 150Copa Airlines06:5008:151h 25mBoeing 737-800
CM 756Copa Airlines08:2009:451h 25mBoeing 737-800

Showing the first 40 of 55 scheduled PTY to MDE departures across 7 days with service, starting October 23, 2026. Every remaining date is on the interactive map.

Departure and arrival times are local at their own airport, so an arrival can fall on a different local date than the departure; the duration column is the true elapsed flying time. A dash means the airline hasn't filed that value in the schedule data we hold. Aircraft are the equipment the airline filed, named where the code pins down one type and shown as the family or the bare code where it doesn't. Swaps can happen up to departure.

See every PTY to MDE date on the interactive map

Aircraft on the Panama City to Medellin nonstop

Copa Airlines flies the departures in the schedule table on this page with the Boeing 737-800, the Boeing 737 MAX 9, and the Boeing 737-700. Each linked aircraft page shows where that airline schedules it. Airlines can swap aircraft up to departure.

The full PTY to MDE nonstop schedule

This page carries the full PTY to MDE nonstop schedule, who operates each departure and how often it runs; the reverse direction is linked below.

See the schedule

Who operates each PTY to MDE nonstop and how often it runs, from 2LNR's schedule data.

Plan on the map

See PTY to MDE on the interactive route map, with schedules, connections, and route statistics.

Airlines flying Panama City to Medellin nonstop

Carriers operating PTY to MDE nonstop in the current schedule.

See PTY to MDE on the interactive map →

Frequently asked questions about PTY to MDE

How long is the flight from Panama City (PTY) to Medellin (MDE)?
Scheduled flight times from Panama City (PTY) to Medellin (MDE) run from 1h 25m to 1h 26m across the departures in the schedule table on this page. The nonstop covers about 337 miles, and airlines adjust scheduled times by season, so confirm with the airline before you book.
Which airlines fly nonstop from PTY to MDE?
Copa Airlines is currently the only airline flying PTY to MDE nonstop. 2LNR doesn't show award or upgrade space for it on PTY to MDE, so this page carries the schedule rather than a space claim.
How many flights a week are there from PTY to MDE?
About 56 nonstop flights a week run between Panama City (PTY) and Medellin (MDE) in the current schedule, operated by Copa Airlines. Frequency shifts by season, and the schedule table on this page shows what is scheduled next.
What time do flights from PTY to MDE depart?
Scheduled PTY to MDE nonstops in the next 7 days with service leave between 06:50 and 21:25, local time at Panama City. The schedule table on this page lists every departure by date, with its arrival time and aircraft.
Which flights operate PTY to MDE nonstop?
The schedule table on this page lists 9 flight numbers for PTY to MDE nonstops, including CM 150, CM 155, CM 156, CM 208, CM 397, CM 654, CM 756, and CM 764 on Copa Airlines. The table lists each departure by date with its times and aircraft.
Does 2LNR show upgrade or award space on PTY to MDE?
Not on this route: 2LNR doesn't show award or upgrade space for Copa Airlines on PTY to MDE. The page carries the full PTY to MDE nonstop schedule and who flies each departure, and the reverse direction is linked below.

See the full PTY to MDE nonstop schedule

Every scheduled departure on this route, with who flies it. 2LNR shows upgrade and award space by date on the carriers it tracks, the next 14 days free on every product and the full horizon on Pro.

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