Direct flights from Knoxville (TYS)

From McGhee Tyson Airport (TYS), 4 airlines fly nonstop to 33 destinations, led by Allegiant Air, American Airlines, and Delta Air Lines. The busiest nonstops from Knoxville go to Chicago, Dallas, and Atlanta. 2LNR monitors confirmed space on the Knoxville routes flown by American Airlines and Delta Air Lines so you can act while it's still available.

Route data refreshed October 23, 2026. Routes and carriers reflect the schedule data behind 2LNR's route map.

Updated October 23, 2026.

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Nonstop destinations

Airlines serving TYS

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About McGhee Tyson Airport (TYS)

McGhee Tyson Airport (TYS) is the airport serving Knoxville, United States. Its ICAO code is KTYS. Departure and arrival times at TYS are local to the America/New_York time zone. Every one of its 33 nonstop destinations is inside United States.

Confirmed upgrade & award space on Knoxville routes

2LNR tracks confirmed upgrade and award space on American Airlines and Delta Air Lines, segment by segment and date by date. Pick any Knoxville destination below to open a calendar of departures, the next 14 days free on every product and the full horizon on Pro.

See real availability

Confirmed upgrade or award seats by date on the TYS routes 2LNR tracks, checked against live inventory so you know what's open before you book.

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Premium inventory turns over fast. Watch a tracked Knoxville route on Pro and 2LNR notifies you when space appears.

Plan on the map

Explore every TYS nonstop on the interactive route map, with connections and route statistics.

All nonstop destinations from Knoxville (TYS)

These are the city pairs behind flights to and from Knoxville: 33 nonstop destinations with active service at McGhee Tyson Airport. Each route links to its own page, with confirmed upgrade or award space by date where 2LNR tracks the carrier.

Knoxville to Atlanta flights (TYS-ATL): Delta Air Lines
Return: Atlanta to Knoxville
Knoxville to Austin flights (TYS-AUS): Allegiant Air
Return: Austin to Knoxville
Knoxville to Baton Rouge flights (TYS-BTR): Delta Air Lines
Return: Baton Rouge to Knoxville
Knoxville to Boston flights (TYS-BOS): Allegiant Air
Return: Boston to Knoxville
Knoxville to Charlotte flights (TYS-CLT): American Airlines
Return: Charlotte to Knoxville
Knoxville to Chicago flights (TYS-MDW): Allegiant Air
Return: Chicago to Knoxville
Knoxville to Chicago flights (TYS-ORD): American Airlines and United Airlines
Return: Chicago to Knoxville
Knoxville to College Station flights (TYS-CLL): American Airlines
Return: College Station to Knoxville
Knoxville to Dallas flights (TYS-DFW): American Airlines
Return: Dallas to Knoxville
Knoxville to Denver flights (TYS-DEN): Allegiant Air and United Airlines
Return: Denver to Knoxville
Knoxville to Detroit flights (TYS-DTW): Delta Air Lines
Return: Detroit to Knoxville
Knoxville to Eglin Village flights (TYS-VPS): Allegiant Air
Return: Eglin Village to Knoxville
Knoxville to Fort Lauderdale flights (TYS-FLL): Allegiant Air
Return: Fort Lauderdale to Knoxville
Knoxville to Houston flights (TYS-HOU): Allegiant Air
Return: Houston to Knoxville
Knoxville to Houston flights (TYS-IAH): United Airlines
Return: Houston to Knoxville
Knoxville to Jacksonville flights (TYS-JAX): Allegiant Air
Return: Jacksonville to Knoxville
Knoxville to Key West flights (TYS-EYW): Allegiant Air
Return: Key West to Knoxville
Knoxville to Las Vegas flights (TYS-LAS): Allegiant Air
Return: Las Vegas to Knoxville
Knoxville to Miami flights (TYS-MIA): American Airlines
Return: Miami to Knoxville
Knoxville to Minneapolis flights (TYS-MSP): Delta Air Lines
Return: Minneapolis to Knoxville
Knoxville to Montrose flights (TYS-MTJ): United Airlines
Knoxville to New Orleans flights (TYS-MSY): American Airlines
Return: New Orleans to Knoxville
Knoxville to New York flights (TYS-LGA): American Airlines and Delta Air Lines
Return: New York to Knoxville
Knoxville to Newark flights (TYS-EWR): Allegiant Air and United Airlines
Return: Newark to Knoxville
Knoxville to Orlando flights (TYS-MCO): Allegiant Air
Return: Orlando to Knoxville
Knoxville to Orlando flights (TYS-SFB): Allegiant Air
Return: Orlando to Knoxville
Knoxville to Philadelphia flights (TYS-PHL): Allegiant Air and American Airlines
Return: Philadelphia to Knoxville
Knoxville to Phoenix flights (TYS-PHX): Allegiant Air
Return: Phoenix to Knoxville
Knoxville to Punta Gorda flights (TYS-PGD): Allegiant Air
Return: Punta Gorda to Knoxville
Knoxville to Sarasota flights (TYS-SRQ): Allegiant Air
Return: Sarasota to Knoxville
Knoxville to South Highpoint flights (TYS-PIE): Allegiant Air
Return: South Highpoint to Knoxville
Knoxville to Washington flights (TYS-DCA): American Airlines and Delta Air Lines
Return: Washington to Knoxville
Knoxville to Washington flights (TYS-IAD): Allegiant Air and United Airlines
Return: Washington to Knoxville

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Nonstop flights to Knoxville (TYS)

32 airports have nonstops to McGhee Tyson Airport in 2LNR's schedule data. Here they are, with the airlines that fly each route.

Atlanta to Knoxville flights (ATL-TYS): Delta Air Lines
Austin to Knoxville flights (AUS-TYS): Allegiant Air
Baton Rouge to Knoxville flights (BTR-TYS): Delta Air Lines
Boston to Knoxville flights (BOS-TYS): Allegiant Air
Charlotte to Knoxville flights (CLT-TYS): American Airlines
Chicago to Knoxville flights (MDW-TYS): Allegiant Air
Chicago to Knoxville flights (ORD-TYS): American Airlines and United Airlines
College Station to Knoxville flights (CLL-TYS): American Airlines
Dallas to Knoxville flights (DFW-TYS): American Airlines
Denver to Knoxville flights (DEN-TYS): Allegiant Air and United Airlines
Detroit to Knoxville flights (DTW-TYS): Delta Air Lines
Eglin Village to Knoxville flights (VPS-TYS): Allegiant Air
Fort Lauderdale to Knoxville flights (FLL-TYS): Allegiant Air
Houston to Knoxville flights (HOU-TYS): Allegiant Air
Houston to Knoxville flights (IAH-TYS): United Airlines
Jacksonville to Knoxville flights (JAX-TYS): Allegiant Air
Key West to Knoxville flights (EYW-TYS): Allegiant Air
Las Vegas to Knoxville flights (LAS-TYS): Allegiant Air
Miami to Knoxville flights (MIA-TYS): American Airlines
Minneapolis to Knoxville flights (MSP-TYS): Delta Air Lines
New Orleans to Knoxville flights (MSY-TYS): American Airlines
New York to Knoxville flights (LGA-TYS): American Airlines and Delta Air Lines
Newark to Knoxville flights (EWR-TYS): Allegiant Air and United Airlines
Orlando to Knoxville flights (MCO-TYS): Allegiant Air
Orlando to Knoxville flights (SFB-TYS): Allegiant Air
Philadelphia to Knoxville flights (PHL-TYS): Allegiant Air and American Airlines
Phoenix to Knoxville flights (PHX-TYS): Allegiant Air
Punta Gorda to Knoxville flights (PGD-TYS): Allegiant Air
Sarasota to Knoxville flights (SRQ-TYS): Allegiant Air
South Highpoint to Knoxville flights (PIE-TYS): Allegiant Air
Washington to Knoxville flights (DCA-TYS): American Airlines and Delta Air Lines
Washington to Knoxville flights (IAD-TYS): Allegiant Air and United Airlines

Airlines that fly out of Knoxville (TYS)

The carriers with nonstop service from McGhee Tyson Airport, ordered by how many destinations each one reaches. Each links to that airline's full route map.

Alternative airports near Knoxville (TYS)

Nearby airports with nonstop service of their own, closest first. Distances are great-circle between the two airports' coordinates, not driving time, so check the ground connection before you treat one as a substitute.

Asheville (AVL) (86 miles, 24 nonstop destinations)
Chattanooga (CHA) (86 miles, 15 nonstop destinations)
Spurgeon (TRI) (100 miles, 6 nonstop destinations)
Greenville (GSP) (119 miles, 17 nonstop destinations)

United States flights by airport

Frequently asked questions about Knoxville (TYS)

How many nonstop destinations does McGhee Tyson Airport (TYS) serve?

McGhee Tyson Airport has active nonstop service to 33 destinations in 2LNR's schedule data. The busiest markets from TYS are Chicago, Dallas, and Atlanta. The full list, with who flies each route and, where 2LNR tracks the carrier, upgrade and award space by date, is on this page.

Which airlines fly out of Knoxville (TYS)?

The carriers with nonstop service from McGhee Tyson Airport are listed in full on this page, each linked to its own route map. Allegiant Air, American Airlines, and Delta Air Lines run the most routes from Knoxville, in that order. In 2LNR's schedule data that is 4 airlines in total.

How many airlines fly out of TYS?

2LNR's schedule data currently shows 4 airlines with at least one nonstop route from Knoxville (TYS). That figure counts the carrier operating the flight rather than every carrier that sells a seat on it, so a codeshare marketed by a partner is not counted twice, and it moves with the season.

How do I check upgrade or award availability from TYS?

Pick any destination on this page, such as Chicago, to open a calendar of TYS departures with confirmed upgrade and award space on American Airlines and Delta Air Lines by date, the next 14 days free on every product and the full horizon on Pro. On Pro you can also set an alert so 2LNR notifies you when space opens.

Does 2LNR track flights from TYS?

Yes. Every nonstop route from McGhee Tyson Airport in 2LNR's schedule data is listed, 33 destinations in total, and on the routes flown by American Airlines and Delta Air Lines what is shown is confirmed availability rather than a forecast, the next 14 days free on every product and the full horizon on Pro.

Where can you fly nonstop from Knoxville (TYS)?

2LNR's schedule data shows nonstops from Knoxville (TYS) to 33 destinations. The busiest go to Chicago, Dallas, Atlanta, Charlotte, Denver, Newark, Houston, Washington, New York, and Detroit. This page lists all 33, with the airlines that fly each one.

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