Knoxville (TYS) to Chicago (ORD) flights: who flies it

Knoxville to Chicago flight schedule

Scheduled nonstop departures for TYS to ORD starting October 23, 2026, last checked against our schedule feed on October 18, 2026. Airlines retime and cancel flights, so confirm with the airline before you book.

Scheduled nonstop departures from Knoxville (TYS) to Chicago (ORD)
Date	Flight	Airline	Departs TYS	Arrives ORD	Duration	Aircraft
Fri, Oct 23	UA 1553	United Airlines	06:00	06:56	1h 56m	Airbus A320
Fri, Oct 23	AA 4751	American Airlines	07:30	08:39	2h 9m	Embraer E175
Fri, Oct 23	UA 1577	United Airlines	10:42	11:40	1h 58m	Airbus A319
Fri, Oct 23	AA 4229	American Airlines	11:35	12:37	2h 2m	Embraer E175
Fri, Oct 23	UA 4548	United Airlines	13:55	14:55	2h	CR5
Fri, Oct 23	AA 3501	American Airlines	17:07	18:09	2h 2m	Embraer E175
Fri, Oct 23	UA 5869	United Airlines	18:03	19:05	2h 2m	CR5
Fri, Oct 23	AA 3547	American Airlines	18:55	20:03	2h 8m	Embraer E175
Sat, Oct 24	UA 1553	United Airlines	06:00	06:56	1h 56m	Airbus A320
Sat, Oct 24	AA 4751	American Airlines	07:30	08:39	2h 9m	Embraer E175
Sat, Oct 24	UA 1577	United Airlines	10:42	11:40	1h 58m	Airbus A319
Sat, Oct 24	AA 4229	American Airlines	11:35	12:37	2h 2m	Embraer E175
Sat, Oct 24	UA 4548	United Airlines	13:55	14:55	2h	CR5
Sat, Oct 24	AA 3501	American Airlines	16:38	17:40	2h 2m	Embraer E175
Sat, Oct 24	AA 6445	American Airlines	16:47	17:59	2h 12m	Bombardier CRJ-700
Sat, Oct 24	UA 5869	United Airlines	18:03	19:05	2h 2m	CR5
Sat, Oct 24	AA 3547	American Airlines	18:55	20:03	2h 8m	Embraer E170
Sun, Oct 25	UA 5524	United Airlines	06:45	07:54	2h 9m	Embraer E175
Sun, Oct 25	UA 5756	United Airlines	07:00	07:55	1h 55m	Embraer E175
Sun, Oct 25	AA 4751	American Airlines	07:30	08:39	2h 9m	Embraer E175
Sun, Oct 25	UA 4581	United Airlines	10:43	11:49	2h 6m	CR5
Sun, Oct 25	AA 4229	American Airlines	11:35	12:37	2h 2m	Embraer E175
Sun, Oct 25	UA 4460	United Airlines	13:59	15:00	2h 1m	CR5
Sun, Oct 25	AA 6445	American Airlines	16:57	18:09	2h 12m	Bombardier CRJ-700
Sun, Oct 25	AA 3501	American Airlines	17:07	18:09	2h 2m	Embraer E175
Sun, Oct 25	UA 5478	United Airlines	17:40	18:41	2h 1m	CR5
Sun, Oct 25	AA 3547	American Airlines	18:55	20:03	2h 8m	Embraer E170
Mon, Oct 26	UA 5524	United Airlines	06:45	07:54	2h 9m	Embraer E175
Mon, Oct 26	UA 5756	United Airlines	07:00	07:55	1h 55m	Embraer E175
Mon, Oct 26	AA 4751	American Airlines	07:30	08:39	2h 9m	Embraer E175
Mon, Oct 26	UA 4581	United Airlines	10:43	11:49	2h 6m	CR5
Mon, Oct 26	UA 5921	United Airlines	10:48	11:54	2h 6m	CR5
Mon, Oct 26	AA 4229	American Airlines	11:35	12:37	2h 2m	Embraer E175
Mon, Oct 26	UA 4460	United Airlines	13:59	15:00	2h 1m	CR5
Mon, Oct 26	AA 6445	American Airlines	16:57	18:09	2h 12m	Bombardier CRJ-700
Mon, Oct 26	AA 3501	American Airlines	17:07	18:09	2h 2m	Embraer E175
Mon, Oct 26	UA 5478	United Airlines	17:40	18:43	2h 3m	Embraer E175
Mon, Oct 26	AA 3547	American Airlines	18:55	20:03	2h 8m	Embraer E170
Tue, Oct 27	UA 5524	United Airlines	06:45	07:54	2h 9m	Embraer E175
Tue, Oct 27	UA 5756	United Airlines	07:00	07:55	1h 55m	Embraer E175

Showing the first 40 of 68 scheduled TYS to ORD departures across 7 days with service, starting October 23, 2026. Every remaining date is on the interactive map.

Departure and arrival times are local at their own airport, so an arrival can fall on a different local date than the departure; the duration column is the true elapsed flying time. A dash means the airline hasn't filed that value in the schedule data we hold. Aircraft are the equipment the airline filed, named where the code pins down one type and shown as the family or the bare code where it doesn't. Swaps can happen up to departure.

See every TYS to ORD date on the interactive map

Aircraft on the Knoxville to Chicago nonstop

In the schedule table on this page, United Airlines flies the Bombardier CRJ, the Embraer E175, the Airbus A320, and the Airbus A319, and American Airlines flies the Embraer E175, the Bombardier CRJ-700, and the Embraer E170. Each linked aircraft page shows where that airline schedules it. Airlines can swap aircraft up to departure.

Confirmed upgrade & award space on TYS to ORD departures

2LNR tracks confirmed upgrade and award space on American Airlines, segment by segment and date by date. Open the calendar for Knoxville to Chicago to see which departures have space, the next 14 days free on every product and the full horizon on Pro.

American Airlines award space was open on 8 of the 14 Knoxville to Chicago departure dates from October 19 to November 1 that 2LNR checked in the 7 days to October 19, 2026.

See real availability

Confirmed upgrade or award seats by date on the TYS to ORD departures 2LNR tracks, checked against live inventory so you know what's open before you book.

Set an alert

Premium inventory turns over fast. Watch this route on Pro and 2LNR notifies you when space appears on a date you're tracking.

Plan on the map

See TYS to ORD on the interactive route map, with schedules, connections, and route statistics.

Airlines flying Knoxville to Chicago nonstop

Carriers operating TYS to ORD nonstop in the current schedule. Where 2LNR tracks the carrier, its departures show confirmed upgrade or award space by date.

See TYS to ORD on the interactive map →

Frequently asked questions about TYS to ORD

How long is the flight from Knoxville (TYS) to Chicago (ORD)?

Scheduled flight times from Knoxville (TYS) to Chicago (ORD) run from 1h 55m to 2h 12m across the departures in the schedule table on this page. The nonstop covers about 475 miles, and airlines adjust scheduled times by season, so confirm with the airline before you book.

Which airlines fly nonstop from TYS to ORD?

United Airlines and American Airlines fly TYS to ORD nonstop. 2LNR tracks confirmed upgrade and award space on American Airlines.

How many flights a week are there from TYS to ORD?

About 78 nonstop flights a week run between Knoxville (TYS) and Chicago (ORD) in the current schedule, operated by United Airlines and American Airlines. Frequency shifts by season, and the schedule table on this page shows what is scheduled next.

What time do flights from TYS to ORD depart?

Scheduled TYS to ORD nonstops in the next 7 days with service leave between 06:00 and 18:55, local time at Knoxville. The schedule table on this page lists every departure by date, with its arrival time and aircraft.

Which flights operate TYS to ORD nonstop?

The schedule table on this page lists 15 flight numbers for TYS to ORD nonstops, including UA 1553, UA 5524, and UA 5756 on United Airlines, and AA 3501, AA 3547, AA 4229, AA 4751, and AA 6445 on American Airlines. The table lists each departure by date with its times and aircraft.

How do I check upgrade or award availability on TYS to ORD?

Open the TYS to ORD route on the interactive map or the matrix to see confirmed upgrade and award space by date on American Airlines, the next 14 days free and the full horizon on Pro. On Pro you can also set an alert on the route and 2LNR notifies you when space opens.