Medellin to Guayaquil (MDE-GYE): nonstop flights and who flies them
Avianca flies nonstop from Medellin (MDE) to Guayaquil (GYE) just three times a week. In the timetable below it flies as AV 8399, scheduled at 1h 55m for the 651 miles.
Schedule last confirmed . Departure times come from 2LNR's schedule data; confirm with the airline before you book.
Updated .
Medellin to Guayaquil flight schedule
Scheduled nonstop departures for MDE to GYE starting October 28, 2026, last checked against our schedule feed on October 25, 2026. Airlines retime and cancel flights, so confirm with the airline before you book.
Schedule data dated .
| Date | Flight | Airline | Departs MDE | Arrives GYE | Duration | Aircraft |
|---|---|---|---|---|---|---|
| AV 8399 | Avianca | 16:50 | 18:45 | 1h 55m | Airbus A320 | |
| AV 8399 | Avianca | 16:50 | 18:45 | 1h 55m | Airbus A320neo | |
| AV 8399 | Avianca | 16:50 | 18:45 | 1h 55m | Airbus A320neo | |
| AV 8399 | Avianca | 16:50 | 18:45 | 1h 55m | Airbus A320neo | |
| AV 8399 | Avianca | 16:50 | 18:45 | 1h 55m | Airbus A320neo | |
| AV 8399 | Avianca | 16:50 | 18:45 | 1h 55m | Airbus A320neo | |
| AV 8399 | Avianca | 16:50 | 18:45 | 1h 55m | Airbus A320neo |
Showing all 7 scheduled MDE to GYE departures across 7 days with service, starting October 28, 2026. Later dates are on the interactive map.
Departure and arrival times are local at their own airport, so an arrival can fall on a different local date than the departure; the duration column is the true elapsed flying time. A dash means the airline hasn't filed that value in the schedule data we hold. Aircraft are the equipment the airline filed, named where the code pins down one type and shown as the family or the bare code where it doesn't. Swaps can happen up to departure.
Aircraft on the Medellin to Guayaquil nonstop
Avianca flies the departures in the schedule table on this page with the Airbus A320neo and the Airbus A320. Each linked aircraft page shows where that airline schedules it. Airlines can swap aircraft up to departure.
The full MDE to GYE nonstop schedule
This page carries the full MDE to GYE nonstop schedule, who operates each departure and how often it runs; the reverse direction is linked below.
See the schedule
Who operates each MDE to GYE nonstop and how often it runs, from 2LNR's schedule data.
Plan on the map
See MDE to GYE on the interactive route map, with schedules, connections, and route statistics.
Airlines flying Medellin to Guayaquil nonstop
Carriers operating MDE to GYE nonstop in the current schedule.
Frequently asked questions about MDE to GYE
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See the full MDE to GYE nonstop schedule
Every scheduled departure on this route, with who flies it. 2LNR shows upgrade and award space by date on the carriers it tracks, the next 14 days free on every product and the full horizon on Pro.
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