Mexico City to Santiago (MEX-SCL): nonstop flights and who flies them

LATAM Chile and Aeroméxico fly the MEX to SCL nonstop about 12 times a week. The timetable below shows the nonstop scheduled at 8h 10m to 8h 50m for the 4,099 miles.

Schedule last confirmed . Departure times come from 2LNR's schedule data; confirm with the airline before you book.

Updated .

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12
Flights a week, 4-week average
8h 10m to 8h 50m
Scheduled flight time
4,099 mi
Nonstop distance
Free
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Mexico City to Santiago flight schedule

Scheduled nonstop departures for MEX to SCL starting October 23, 2026, last checked against our schedule feed on October 18, 2026. Airlines retime and cancel flights, so confirm with the airline before you book.

Schedule data dated .

Scheduled nonstop departures from Mexico City (MEX) to Santiago (SCL)
Date Flight Airline Departs MEX Arrives SCL Duration Aircraft
LA 621LATAM Chile20:0507:558h 50m330
LA 621LATAM Chile19:5007:308h 40m330
AM 10Aeroméxico19:3506:458h 10mBoeing 787-9 Dreamliner
LA 621LATAM Chile19:5007:308h 40m330
LA 621LATAM Chile19:5007:008h 10mBoeing 787-8 Dreamliner
AM 10Aeroméxico09:5521:158h 20mBoeing 787-9 Dreamliner
LA 621LATAM Chile19:5007:008h 10mBoeing 787-8 Dreamliner
AM 10Aeroméxico09:5521:158h 20mBoeing 787-9 Dreamliner
LA 621LATAM Chile19:5007:008h 10mBoeing 787-8 Dreamliner
AM 10Aeroméxico09:5521:158h 20mBoeing 787-9 Dreamliner
LA 621LATAM Chile19:5007:008h 10mBoeing 787-8 Dreamliner

Showing all 11 scheduled MEX to SCL departures across 7 days with service, starting October 23, 2026. Later dates are on the interactive map.

Departure and arrival times are local at their own airport, so an arrival can fall on a different local date than the departure; the duration column is the true elapsed flying time. A dash means the airline hasn't filed that value in the schedule data we hold. Aircraft are the equipment the airline filed, named where the code pins down one type and shown as the family or the bare code where it doesn't. Swaps can happen up to departure.

See every MEX to SCL date on the interactive map

Aircraft on the Mexico City to Santiago nonstop

In the schedule table on this page, LATAM Chile flies the Boeing 787-8 Dreamliner and the Airbus A330, and Aeroméxico flies the Boeing 787-9 Dreamliner. Each linked aircraft page shows where that airline schedules it. Airlines can swap aircraft up to departure.

The full MEX to SCL nonstop schedule

This page carries the full MEX to SCL nonstop schedule, who operates each departure and how often it runs; the reverse direction is linked below.

See the schedule

Who operates each MEX to SCL nonstop and how often it runs, from 2LNR's schedule data.

Plan on the map

See MEX to SCL on the interactive route map, with schedules, connections, and route statistics.

Airlines flying Mexico City to Santiago nonstop

Carriers operating MEX to SCL nonstop in the current schedule.

See MEX to SCL on the interactive map →

Frequently asked questions about MEX to SCL

How long is the flight from Mexico City (MEX) to Santiago (SCL)?
Scheduled flight times from Mexico City (MEX) to Santiago (SCL) run from 8h 10m to 8h 50m across the departures in the schedule table on this page. The nonstop covers about 4,099 miles, and airlines adjust scheduled times by season, so confirm with the airline before you book.
Which airlines fly nonstop from MEX to SCL?
LATAM Chile and Aeroméxico fly MEX to SCL nonstop. 2LNR doesn't show award or upgrade space for any of them on MEX to SCL, so this page carries the schedule rather than a space claim.
How many flights a week are there from MEX to SCL?
About 12 nonstop flights a week run between Mexico City (MEX) and Santiago (SCL) in the current schedule, operated by LATAM Chile and Aeroméxico. Frequency shifts by season, and the schedule table on this page shows what is scheduled next.
What time do flights from MEX to SCL depart?
Scheduled MEX to SCL nonstops in the next 7 days with service leave between 09:55 and 20:05, local time at Mexico City. The schedule table on this page lists every departure by date, with its arrival time and aircraft.
Which flights operate MEX to SCL nonstop?
In the schedule table on this page, MEX to SCL nonstops fly as LA 621 on LATAM Chile and AM 10 on Aeroméxico. The table lists each departure by date with its times and aircraft.
Does 2LNR show upgrade or award space on MEX to SCL?
Not on this route: 2LNR doesn't show award or upgrade space for any airline flying MEX to SCL. The page carries the full MEX to SCL nonstop schedule and who flies each departure, and the reverse direction is linked below.

See the full MEX to SCL nonstop schedule

Every scheduled departure on this route, with who flies it. 2LNR shows upgrade and award space by date on the carriers it tracks, the next 14 days free on every product and the full horizon on Pro.

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